144 0002060075 XXXXXXXX LIVE 0001815442 KYMERA THERAPEUTICS, INC. 001-39460 500 North Beacon Street 4th Floor Watertown MA 02472 (857)-285-5300 Noah Goodman Officer Common Stock Morgan Stanley Smith Barney LLC

1 New York Plaza 38th Floor New York NY 10004

11611 1014221 81642394 04/09/2026 NASDAQ Common Stock 04/09/2026 Shares acquired upon vesting of Restricted Stock Units awarded under the Issuer's 2020 Equity Incentive Plan. KYMERA THERAPEUTICS, INC. N 9111 04/09/2026 Equity compensation Common Stock 04/09/2026 Exercise of Stock Options KYMERA THERAPEUTICS, INC. N 2500 04/09/2026 Cash Y The securities to be sold were acquired upon the vesting of restricted stock units on 4/8/2026 or were received upon the exercise of stock options. The dates of acquisition and payment were and will be the dates of exercise/sale. Certain sales reported on this Form 144 represent shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. These sales are automatic and intended to qualify under Rule 10b5-1. Other sales are pursuant to a 10b5-1 plan entered into on December 10, 2025. 04/09/2026 /s/ Bruce Jacobs