Income Taxes - Schedule of Significant Components of Net Deferred Income Taxes (Details) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Deferred Tax Assets:
Net operating loss carryforwards	$ 159,311	$ 61,531
Research and development credit carryforwards	54,742	42,549
Lease liabilities	21,716	22,980
Deferred revenue	0	3,603
Accruals and reserves, stock and other	18,633	18,794
Capitalized Research and Development	96,991	110,333
Total deferred tax assets	351,393	259,790
Valuation allowance	(330,285)	(236,206)
Total deferred tax assets, net of valuation allowance	21,108	23,584
Deferred Tax Liabilities, Net [Abstract]
Operating right-of-use assets	(9,477)	(10,632)
Depreciation	(11,631)	(12,952)
Total deferred tax liabilities	(21,108)	(23,584)
Net deferred tax asset	$ 0	$ 0