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Income Taxes - Rate Reconciliation of U.S. Statutory Income Tax Rate to Company's Effective Tax Rate (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Income Tax Disclosure [Abstract]      
Federal statutory income tax rate 21.00% 21.00% 21.00%
State income taxes, net of federal income tax effect 0.00% 7.90% 6.80%
Federal research and development credits 2.20% 6.10% 4.60%
Change in valuation allowance (23.20%) (33.00%) (28.60%)
Stock-based compensation 3.00% 0.30% (1.50%)
Excess tax benefits on share-based payments (0.03)    
Disallowed Expenditures   (2.30%) (2.30%)
Other 0.00%    
Total 0.00% 0.00% 0.00%
Federal statutory income tax rate $ (65,384)    
State income taxes, net of federal income tax effect (99)    
Research and development tax credits (6,982)    
Changes in valuation allowances 72,265    
Excess tax benefits on share-based payments 9,485    
Stock-based compensation (9,407)    
Other 122    
Total loss before income taxes $ 0