Equity-Based Compensation - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023	Mar. 31, 2025	Aug. 20, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	$ 59,904	$ 55,012	$ 43,118
Research and Development Expense
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	31,522	27,766	21,555
General and Administrative Expense
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	28,382	27,246	21,563
Employee Stock Option
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Intrinsic value of stock options exercised	$ 95,000	$ 21,800	$ 9,100
Weighted-average fair value of options granted	$ 23.43	$ 26.1	$ 17.91
Unrecognized stock-based compensation expense	$ 63,400
Unrecognized compensation cost, recognition period	2 years 1 month 6 days
Equity-based compensation expense	$ 47,606	$ 46,131	$ 38,550
Employee Stock Option | Research and Development Expense
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	22,773	21,965	18,525
Employee Stock Option | General and Administrative Expense
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	$ 24,833	$ 24,166	$ 20,025
Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Unrecognized compensation cost, recognition period	2 years 6 months
Granted	796,350	400,917	404,844
Unrecognized stock-based compensation expense	$ 28,900
Equity-based compensation expense	11,200	$ 7,700	$ 3,800
Restricted Stock | Research and Development Expense
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	8,100	4,800	2,500
Restricted Stock | General and Administrative Expense
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	$ 3,100	$ 2,900	$ 1,300
2020 Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares authorized for issuance under plan					4,457,370
Maximum number of shares to be issued, percentage	4.00%
Shares remaining available for future grants	4,182,654
Performance stock options vesting				40.00%
Granted	88,000
Second clinical milestone vesting percentage				40.00%
Third clinical milestone vesting percentage				20.00%
Strike price	$ 30.17
Performance stock options outstanding	88,000
2020 Plan | Minimum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range				0.00%
2020 Plan | Maximum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range				100.00%
2020 Plan | Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Granted	285,723	0
2020 Plan | Performance Shares
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options vesting				40.00%
Second clinical milestone vesting percentage				40.00%
Third clinical milestone vesting percentage				20.00%
Strike price	$ 30.17
2020 Plan | Performance Shares | Minimum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range				0.00%
2020 Plan | Performance Shares | Maximum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range				100.00%
2020 ESPP
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares authorized for issuance under plan					445,653
Shares remaining available for future grants	2,303,412
Share-based compensation, description	The 2020 ESPP provides that the number of shares reserved and available for issuance will automatically increase on January 1, 2021 and each January 1 thereafter through January 1, 2030, by the lessor of (i) 438,898 shares of common stock, (ii) 1% of the Company’s outstanding number of shares of common stock on the immediately preceding December 31 or (iii) such lesser number of shares of common stock as determined by the administrator of the 2020 ESPP.
2020 ESPP | Lesser of Potential Outcome 1
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of additional shares authorized	438,898
2020 ESPP | Lesser of Potential Outcome 2
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Maximum number of shares to be issued, percentage	1.00%
2018 Plan | Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Granted	1,082,073