Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands		12 Months Ended
		Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Collaboration revenue		$ 39,211	$ 47,072	$ 78,592
Revenue from Contract with Customer, Product and Service [Extensible List]		us-gaap:RelatedPartyMember	us-gaap:RelatedPartyMember	us-gaap:RelatedPartyMember
Operating expenses:
Research and development		$ 316,568	$ 240,248	$ 189,081
General and administrative	[1]	68,187	63,534	55,041
Impairment of long-lived assets		3,855	4,925	0
Total operating expenses		388,610	308,707	244,122
Loss from operations		(349,399)	(261,635)	(165,530)
Other income (expense):
Interest and other income		38,418	38,026	18,764
Interest and other expense		(370)	(249)	(196)
Total other income		38,048	37,777	18,568
Net loss		(311,351)	(223,858)	(146,962)
Other comprehensive loss:
Unrealized gain (loss) on marketable securities		3,285	(933)	4,397
Total comprehensive loss		(308,066)	(224,791)	(142,565)
Reconciliation of net loss to net loss attributable to common stockholders:
Net Income (Loss)		(311,351)	(223,858)	(146,962)
Net loss attributable to common stockholders		$ (311,351)	$ (223,858)	$ (146,962)
Net loss per share, basic		$ (3.69)	$ (2.98)	$ (2.52)
Net loss per share, diluted		$ (3.69)	$ (2.98)	$ (2.52)
Total weighted average common stock outstanding, basic and diluted		84,490,585	75,043,991	58,365,499
Total weighted average common stock outstanding, basic and diluted		84,490,585	75,043,991	58,365,499

[1] (3) General and administrative expense for the years ended December 31, 2025, 2024 and 2023 is inclusive of $28.4 million, $27.2 million, and $21.6 million of stock-based compensation expense, respectively.