Segment Reporting - Schedule of Segment Reporting Presents Reportable Segment Profit and Loss (Details) - USD ($) $ in Thousands		3 Months Ended
		Mar. 31, 2025	Mar. 31, 2024
Revenue		$ 22,100	$ 10,287
Revenue		22,100	10,287
Less:
Research and development		80,255	48,819
Other external research and development expense	[1]	16,292	11,697
Research and development compensation and related personnel expense	[2]	22,049	18,866
Research and development overhead and administrative costs		11,223	9,257
General and administrative	[3]	16,271	14,374
Interest and other expense	[4]	72	4,994
Plus: [Abstract]
Interest income		8,917	9,343
Segment net loss		(65,581)	(48,557)
STAT6 [Member]
Less:
Research and development		20,605	3,918
TYK2 [Member]
Less:
Research and development		8,893	3,271
IRAK4 [Member]
Less:
Research and development		$ 1,193	$ 1,810

[1] Certain prior period amounts have been recast to conform with current period presentation.

[2] Research and development compensation and related personnel expense for the quarter ended March 31, 2025 and 2024 is inclusive of $7.5 and $6.1 million of stock-based compensation expense, respectively.

[3] General and administrative expense for the quarter ended March 31, 2025 and 2024 is inclusive of $6.7 million and $5.9 million of stock-based compensation expense, respectively.

[4] Other expense for the quarter ended March 31, 2024 is inclusive of a $4.9 million impairment of long-lived assets.