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Amount of cost to be recognized for nonvested award under share-based payment arrangement. Excludes share and unit options.

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Number of additional shares authorized for issuance under share-based payment arrangement.

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Number of shares authorized for issuance under share-based payment arrangement.

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The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable.

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Amount of accumulated difference between fair value of underlying shares on dates of exercise and exercise price on options exercised (or share units converted) into shares.

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The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology.

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Maximum number of shares that may be issued in accordance with the plan as a proportion of outstanding capital stock.

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Equity-Based Compensation - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024	Aug. 20, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	$ 14,234	$ 11,968
Research and Development Expense
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	7,546	6,083
General and Administrative
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	6,688	5,885
Employee Stock Option
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Intrinsic value of stock options exercised	$ 2,100	$ 6,800
Weighted-average fair value of options granted	$ 20.66	$ 26.53
Unrecognized stock-based compensation expense	$ 87,900
Unrecognized compensation cost, recognition period	2 years 2 months 12 days
Equity-based compensation expense	$ 11,570	$ 10,362
Employee Stock Option \| Research and Development Expense
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	5,713	5,040
Employee Stock Option \| General and Administrative
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	5,857	$ 5,322
Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Unrecognized stock-based compensation expense	$ 24,600
Unrecognized compensation cost, recognition period	2 years 4 months 24 days
Granted	327,800	231,834
Equity-based compensation expense	$ 2,400	$ 1,400
Restricted Stock \| Research and Development Expense
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	1,600	900
Restricted Stock \| General and Administrative
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity-based compensation expense	800	$ 500
Performance Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Unrecognized stock-based compensation expense	$ 0
2020 Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares authorized for issuance under plan			4,457,370
Maximum number of shares to be issued, percentage	4.00%
Shares remaining available for future grants	4,606,684
Performance stock options vesting	40.00%
Second clinical milestone vesting percentage	40.00%
Third clinical milestone vesting percentage	20.00%
Granted	88,000
Option Indexed to Issuer's Equity, Strike Price	$ 30.17
Performance stock options outstanding	88,000
2020 Plan \| Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Granted	285,723	0
2020 Plan \| Performance Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options vesting	40.00%
Second clinical milestone vesting percentage	40.00%
Third clinical milestone vesting percentage	20.00%
Option Indexed to Issuer's Equity, Strike Price	$ 30.17
2020 Plan \| Minimum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range	0.00%
2020 Plan \| Minimum [Member] \| Performance Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range	0.00%
2020 Plan \| Maximum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range	100.00%
2020 Plan \| Maximum [Member] \| Performance Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range	100.00%
2020 ESPP
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares authorized for issuance under plan			445,653
Shares remaining available for future grants	2,363,127
Share-based compensation, description	The 2020 ESPP initially reserved and authorized the issuance of up to a total of 445,653 shares of common stock to participating employees. The 2020 ESPP provides that the number of shares reserved and available for issuance will automatically increase on January 1, 2021 and each January 1 thereafter through January 1, 2030, by the lesser of (i) 438,898 shares of common stock, (ii) 1% of the Company’s outstanding number of shares of common stock on the immediately preceding December 31 or (iii) such lesser number of shares of common stock as determined by the administrator of the 2020 ESPP
2020 ESPP \| Lesser of Potential Outcome 1
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Maximum number of shares to be issued, percentage	1.00%
Number of additional shares authorized	438,898
2018 Plan \| Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Granted	613,523