Organization and Nature of Business - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands			3 Months Ended
	Aug. 21, 2024	Jan. 09, 2024	Mar. 31, 2025	Mar. 31, 2024	Dec. 31, 2024
Organization and Nature of Business [Line Items]
Accumulated deficit			$ 820,191		$ 754,610
Cash, cash equivalents and marketable securities			$ 775,500
Aggregate proceeds from issuance of private placement				$ 14,900
Common Stock Per Share Exercise Price			$ 0.0001		$ 0.0001
Pre-funded warrants
Organization and Nature of Business [Line Items]
Pre-funded warrants outstanding			15,159,753	11,640,594
Warrants exercised			0
Increase or decrease pre-funded warrants, maximum			19.99%
Minimum pre-funded warrants, exercise			4.99%
Maximum pre-funded warrants, exercise			9.99%
Prior notice period, minimum			61 days
Common Stock | Pre-funded warrants
Organization and Nature of Business [Line Items]
Common Stock Per Share Exercise Price			$ 0.0001
Underwriters
Organization and Nature of Business [Line Items]
Stock Issued During Period, Shares, New Issues	828,220	1,633,663
2024 Follow-on Public Offerings
Organization and Nature of Business [Line Items]
Stock Issued During Period, Shares, New Issues	2,830,533	3,884,158
Common stock per share	$ 40.75	$ 25.25
Aggregate Gross Proceeds	$ 258,700	$ 316,200
2024 Follow-on Public Offerings | Pre-funded warrants
Organization and Nature of Business [Line Items]
Pre-funded warrant purchase price	$ 40.7499	$ 25.2499
2024 Follow-on Public Offerings | Common Stock | Pre-funded warrants
Organization and Nature of Business [Line Items]
Number of Common Stock Purchased in Place of Pre funded Warrants	3,519,159	8,640,594
Common Stock Per Share Exercise Price	$ 0.0001	$ 0.0001