Segment Reporting (Tables)

3 Months Ended

Mar. 31, 2025

Segment Reporting [Abstract]

Schedule of Segment Reporting Presents Reportable Segment Profit and Loss

The following table presents reportable segment profit and loss, including significant expense categories, attributable to the Company’s reportable segment for the periods presented:

	Three Months Ended March 31,
	2025			2024
Revenue	$	22,100		$	10,287
Less:
Research and development expenses
External research and development:
STAT6		20,605			3,918
TYK2		8,893			3,271
IRAK4		1,193			1,810
Other external research and development expense (1)		16,292			11,697
Research and development compensation and related personnel expense (2)		22,049			18,866
Research and development overhead and administrative costs		11,223			9,257
General & administrative (3)		16,271			14,374
Interest and other expense (4)		72			4,994
Plus:
Interest income		8,917			9,343
Segment net loss	$	(65,581	)	$	(48,557	)

(1) Certain prior period amounts have been recast to conform with current period presentation.

(2) Research and development compensation and related personnel expense for the quarter ended March 31, 2025 and 2024 is inclusive of $7.5 and $6.1 million of stock-based compensation expense, respectively.

(3) General and administrative expense for the quarter ended March 31, 2025 and 2024 is inclusive of $6.7 million and $5.9 million of stock-based compensation expense, respectively.

(4) Other expense for the quarter ended March 31, 2024 is inclusive of a $4.9 million impairment of long-lived assets.