Segment Reporting - Schedule of Segment Reporting Presents Reportable Segment Profit and Loss (Details) - USD ($) $ in Thousands		12 Months Ended
		Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Segment Reporting Information [Line Items]
Revenue		$ 47,072	$ 78,592	$ 46,826
Less:
Research and Development Expense, Total		240,248	189,081	164,248
Other external research and development expense		43,909	61,278	51,388
Research and development compensation and related personnel expense	[1]	75,975	65,039	55,751
Research and development overhead and administrative costs		39,487	29,342	19,104
General and administrative	[2]	63,534	55,041	43,834
Interest and other expense	[3]	5,174	196	176
Plus:
Interest income		38,026	18,764	6,624
Segment net loss		(223,858)	(146,962)	(154,808)
STAT6 Programs [Member]
Less:
Research and Development Expense, Total		39,805	0	0
TYK2 Programs [Member]
Less:
Research and Development Expense, Total		18,292	0	0
IRAK4 Programs [Member]
Less:
Research and Development Expense, Total		7,065	13,762	17,850
MDM2 Programs [Member]
Less:
Research and Development Expense, Total		8,516	8,170	11,823
STAT3 Programs [Member]
Less:
Research and Development Expense, Total		$ 7,199	$ 11,490	$ 8,332

[1] Research and development compensation and related personnel expense for the years ended December 31, 2024, 2023 and 2022 is inclusive of $27.8 million, $21.6 million, and $18.0 million of stock-based compensation expense, respectively.

[2] General and administrative expense for the years ended December 31, 2024, 2023 and 2022 is inclusive of $27.2 million, $21.6 million, and $17.5 million of stock-based compensation expense, respectively.

[3] Other expense for the year ended December 31, 2024 is inclusive of a $4.9 million impairment of long-lived assets.