Income Taxes - Schedule of Significant Components of Net Deferred Income Taxes (Details) - USD ($) $ in Thousands	Dec. 31, 2024	Dec. 31, 2023
Deferred Tax Assets:
Federal net operating loss carryforwards	$ 46,468	$ 33,708
State net operating loss carryforwards	15,063	10,194
Research and development credit carryforwards	42,549	25,975
Lease liabilities	22,980	22,443
Deferred revenue	3,603	9,807
Accruals and reserves, stock and other	18,794	13,636
Capitalized Research and Development	110,333	68,340
Total deferred tax assets	259,790	184,103
Valuation allowance	(236,206)	(162,375)
Deferred tax assets	23,584	21,728
Fixed and intangible assets	(10,632)	(1,884)
Right-of-use assets	(12,952)	(19,844)
Net deferred tax asset	$ 0	$ 0