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CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (Unaudited) - USD ($)
$ in Thousands
Total
January 2024 [Member]
August 2024 [Member]
Common Stock
Common Stock
January 2024 [Member]
Common Stock
August 2024 [Member]
Additional Paid In Capital
Additional Paid In Capital
January 2024 [Member]
Additional Paid In Capital
August 2024 [Member]
Accumulated Deficit
Accumulated Other Comprehensive Gain (Loss)
Beginning Balance at Dec. 31, 2022 $ 490,151     $ 6     $ 878,884     $ (383,790) $ (4,949)
Shares, Outstanding, Beginning Balance at Dec. 31, 2022       55,039,380              
Issuance of common stock and accompanying pre-funded warrants from public offering, net of issuance costs 0                    
Issuance of common stock and accompanying pre-funded warrants from August 2024 public offering, net of issuance costs of $12.2 million 0                    
Exercise of stock options 2,297           2,297        
Exercise of stock options, Shares       335,065              
Vesting restricted stock, Shares       36,371              
Issuance of shares under employee stock purchase plan 962           962        
Issuance of shares under employee stock purchase plan, Shares       39,423              
Stock-based compensation expense 32,220           32,220        
Unrealized loss on marketable securities 2,499                   2,499
Net loss (132,594)                 (132,594)  
Ending Balance at Sep. 30, 2023 395,535     $ 6     914,363     (516,384) (2,450)
Shares, Outstanding, Ending Balance at Sep. 30, 2023       55,450,239              
Beginning Balance at Jun. 30, 2023 435,428     $ 6     902,574     (463,517) (3,635)
Shares, Outstanding, Beginning Balance at Jun. 30, 2023       55,390,259              
Exercise of stock options 135           135        
Exercise of stock options, Shares       58,373              
Vesting restricted stock, Shares       1,607              
Stock-based compensation expense 11,654           11,654        
Unrealized loss on marketable securities 1,185                   1,185
Net loss (52,867)                 (52,867)  
Ending Balance at Sep. 30, 2023 395,535     $ 6     914,363     (516,384) (2,450)
Shares, Outstanding, Ending Balance at Sep. 30, 2023       55,450,239              
Beginning Balance at Dec. 31, 2023 394,971     $ 6     926,269     (530,752) (552)
Shares, Outstanding, Beginning Balance at Dec. 31, 2023       55,585,305              
Issuance of common stock and accompanying pre-funded warrants from public offering, net of issuance costs (301,373) $ 301,373 $ 246,506     $ 1   $ 301,373 $ 246,505    
Issuance of common stock through At-The Market Sales Agreement, net of issuance costs of $1.2 million, Share       1,519,453              
Issuance of common stock through at-the market sales agreement, net of issuance costs 48,740           48,740        
Issuance of common stock and accompanying pre-funded warrants from August 2024 public offering, net of issuance costs of $12.2 million (246,506)                    
Issuance of common stock and accompanying pre-funded warrants, shares         3,884,158 2,830,533          
Exercise of stock options 9,616           9,616        
Exercise of stock options, Shares       695,821              
Vesting restricted stock, Shares       168,731              
Issuance of shares under employee stock purchase plan 1,134           1,134        
Issuance of shares under employee stock purchase plan, Shares       64,225              
Stock-based compensation expense 41,213           41,213        
Unrealized loss on marketable securities 2,483                   2,483
Net loss (153,106)                 (153,106)  
Ending Balance at Sep. 30, 2024 892,930     $ 7     1,574,850     (683,858) 1,931
Shares, Outstanding, Ending Balance at Sep. 30, 2024       64,748,226              
Beginning Balance at Jun. 30, 2024 684,924     $ 6     1,308,388     (621,371) (2,099)
Shares, Outstanding, Beginning Balance at Jun. 30, 2024       61,572,383              
Issuance of common stock and accompanying pre-funded warrants from public offering, net of issuance costs     $ 246,506     $ 1     $ 246,505    
Issuance of common stock and accompanying pre-funded warrants, shares       2,830,533              
Exercise of stock options 5,053           5,053        
Exercise of stock options, Shares       340,482              
Vesting restricted stock, Shares       4,828              
Stock-based compensation expense 14,904           14,904        
Unrealized loss on marketable securities 4,030                   4,030
Net loss (62,487)                 (62,487)  
Ending Balance at Sep. 30, 2024 $ 892,930     $ 7     $ 1,574,850     $ (683,858) $ 1,931
Shares, Outstanding, Ending Balance at Sep. 30, 2024       64,748,226