Organization and Nature of Business - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands			3 Months Ended
	Jan. 09, 2024	Aug. 18, 2022	Mar. 31, 2024	Dec. 31, 2023
Organization and Nature of Business [Line Items]
Accumulated deficit			$ 579,309	$ 530,752
Cash, cash equivalents and marketable securities			744,900
Aggregate proceeds from issuance of private placement			$ 14,900
Common Stock Per Share Exercise Price			$ 0.0001	$ 0.0001
Pre-funded warrants
Organization and Nature of Business [Line Items]
Pre-funded warrants outstanding			11,640,594
Warrants Exercised			0
Increase or decrease pre-funded warrants, maximum			19.99%
Minimum pre-funded warrants, exercise			4.99%
Maximum pre-funded warrants, exercise			9.99%
Prior notice period, minimum			61 days
Underwriters
Organization and Nature of Business [Line Items]
Issuance of shares, Shares	1,633,663
Private Investment in Public Equity "PIPE"
Organization and Nature of Business [Line Items]
Issuance of shares, Shares		2,769,228
Common stock per share		$ 26
Pre-funded warrants to purchase		$ 3,000,000
Pre-funded warrant purchase price		$ 25.9999
Pre-funded warrants per share		$ 0.0001
Offering expenses		$ 149,800
2024 Follow-on Public Offering
Organization and Nature of Business [Line Items]
Issuance of shares, Shares	3,884,158
Common stock per share	$ 25.25
Aggregate Gross Proceeds	$ 316,200
2024 Follow-on Public Offering | Pre-funded warrants
Organization and Nature of Business [Line Items]
Pre-funded warrant purchase price	$ 25.2499
2024 Follow-on Public Offering | Common Stock | Pre-funded warrants
Organization and Nature of Business [Line Items]
Number of Common Stock Purchased in Place of Pre funded Warrants	8,640,594
Common Stock Per Share Exercise Price	$ 0.0001