Collaborations - Change in Accounts Receivable, Contract Asset and Liabilities (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2023 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts receivable and contract assets, Beginning balance	$ 2,537
Accounts receivable and contract assets, Additions	83,739
Accounts receivable and contract assets, Deductions	(67,514)
Accounts receivable and contract assets, Ending balance	18,762
Contract Liabilities, Beginning balance	63,260
Contract Liabilities, Additions	69,983
Contract Liabilities, Deductions	(78,592)
Contract Liabilities, Ending balance	54,651
Billed Receivables - Sanofi
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts receivable and contract assets, Beginning balance	0
Accounts receivable and contract assets, Additions	68,757
Accounts receivable and contract assets, Deductions	(53,757)
Accounts receivable and contract assets, Ending balance	15,000
Unbilled Receivables - Sanofi
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts receivable and contract assets, Beginning balance	2,537
Accounts receivable and contract assets, Additions	14,982
Accounts receivable and contract assets, Deductions	(13,757)
Accounts receivable and contract assets, Ending balance	3,762
Deferred Revenue - Vertex
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Contract Liabilities, Beginning balance	8,399
Contract Liabilities, Additions	0
Contract Liabilities, Deductions	(8,399)
Contract Liabilities, Ending balance	0
Deferred Revenue - Sanofi
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Contract Liabilities, Beginning balance	54,861
Contract Liabilities, Additions	69,983
Contract Liabilities, Deductions	(70,193)
Contract Liabilities, Ending balance	$ 54,651