Basic and diluted loss per share is computed by dividing net loss by the weighted-average common shares outstanding for the period, including the pre-funded warrants given their nominal exercise price (in thousands, except for share and per share data):


	Three Months Ended March 31,
	2023			2022
Numerator:
Net loss	$	(40,928	)	$	(36,684	)
Denominator:
Weighted average common shares outstanding, basic and diluted		58,187,038			51,651,125
Net loss per share, basic and diluted	$	(0.70	)	$	(0.71	)

The Company’s potentially dilutive securities, which include restricted stock and stock options, have been excluded from the computation of diluted net loss per share as the effect would be to reduce the net loss per share. Therefore, the weighted-average number of common shares outstanding used to calculate both basic and diluted net loss per share attributable to common stockholders is the same. The Company excluded the following from the computation of diluted net loss per share attributable to common stockholders at March 31, 2023 and 2022 because including them would have had an anti-dilutive effect:


	Three Months Ended March 31,
	2023		2022
Unvested restricted stock		452,721		121,504
Options to purchase common stock		8,291,731		7,119,524
Total		8,744,452		7,241,028