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Income Taxes - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Line Items]      
Income tax expense $ 0 $ 0 $ 0
Valuation allowance 120,100,000 78,000,000.0  
Increase of valuation allowance 42,100,000    
Federal net operating loss carryovers, not subject to expiration 144,100,000    
Reserves for uncertain tax positions 0 0  
Estimated interest or penalties recognized on uncertain tax positions $ 0 0  
Earliest Tax Year      
Income Tax Disclosure [Line Items]      
Open tax year subject to examination 2019    
Latest Tax Year      
Income Tax Disclosure [Line Items]      
Open tax year subject to examination 2022    
Federal      
Income Tax Disclosure [Line Items]      
NOL carryforwards $ 153,900,000 123,600,000  
Research and development credit carryforwards 12,700,000 10,400,000  
State      
Income Tax Disclosure [Line Items]      
NOL carryforwards 139,800,000 105,200,000  
Research and development credit carryforwards $ 6,100,000 $ 5,200,000  
Federal and State      
Income Tax Disclosure [Line Items]      
NOLs begin to expire year 2036