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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Collaboration Revenue—from related party $ 46,826 $ 72,832 $ 34,034
Revenue from Contract with Customer, Product and Service [Extensible List] Collaboration Revenues From Related Party [Member] Collaboration Revenues From Related Party [Member] Collaboration Revenues From Related Party [Member]
Operating expenses:      
Research and development $ 164,248 $ 137,017 $ 62,105
General and administrative 43,834 36,345 18,233
Total operating expenses 208,082 173,362 80,338
Loss from operations (161,256) (100,530) (46,304)
Other income (expense):      
Interest and other income 6,624 488 826
Interest and other expense (176) (175) (115)
Total other income 6,448 313 711
Net loss (154,808) (100,217) (45,593)
Other comprehensive loss:      
Unrealized (loss) gain on marketable securities (4,289) (532) (134)
Total comprehensive loss (159,097) (100,749) (45,727)
Reconciliation of net loss to net loss attributable to common stockholders:      
Net Loss (154,808) (100,217) (45,593)
Deemed dividend from exchange of convertible preferred stock 0 0 (9,050)
Net loss attributable to common stockholders $ (154,808) $ (100,217) $ (54,643)
Net loss per share, basic $ (2.87) $ (2.09) $ (3.15)
Net loss per share, diluted $ (2.87) $ (2.09) $ (3.15)
Weighted average common shares outstanding, diluted 53,933,229 47,989,023 17,349,582
Weighted average common shares outstanding, basic 53,933,229 47,989,023 17,349,582