CONDENSED CONSOLIDATED STATEMENTS OF CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS' EQUITY (DEFICIT) (Unaudited) - USD ($) $ in Thousands	Total	Common Stock	Additional Paid In Capital	Accumulated Deficit	Accumulated Other Comprehensive Gain (Loss)
Beginning Balance at Dec. 31, 2020	$ 283,888	$ 4	$ 412,777	$ (128,765)	$ (128)
Shares, Outstanding, Beginning Balance at Dec. 31, 2020		44,482,186
Exercise of stock options	5,875	$ 1	5,874
Exercise of stock options, Shares		1,193,773
Vesting restricted stock, Shares		54,736
Issuance of shares under employee stock purchase plan	307		307
Issuance of shares under employee stock purchase plan, Shares		7,680
Issuance of shares in connection with public offering net of underwriting discounts and costs, Shares		5,468,250
Issuance of shares in connection with public offering net of underwriting discounts and cost	240,760		240,760
Stock-based compensation expense	16,294		16,294
Unrealized gain (loss) on marketable securities	(18)				(18)
Issuance of shares in concurrent private placement,shares		49,928
Issuance of shares in concurrent private placement	2,346		2,346
Net Loss	(66,317)			(66,317)
Ending Balance at Sep. 30, 2021	483,135	$ 5	678,358	(195,082)	(146)
Shares, Outstanding, Ending Balance at Sep. 30, 2021		51,256,553
Beginning Balance at Jun. 30, 2021	258,104	$ 5	424,599	(166,500)
Shares, Outstanding, Beginning Balance at Jun. 30, 2021		45,327,681
Exercise of stock options	3,257	$ 0	3,257
Exercise of stock options, Shares		392,540
Vesting restricted stock, Shares		18,154
Issuance of shares in connection with public offering net of underwriting discounts and costs, Shares		5,468,250
Issuance of shares in connection with public offering net of underwriting discounts and cost	240,760		240,760
Stock-based compensation expense	7,396		7,396
Unrealized gain (loss) on marketable securities	(146)				(146)
Issuance of shares in concurrent private placement,shares		49,928
Issuance of shares in concurrent private placement	2,346		2,346
Net Loss	(28,582)			(28,582)
Ending Balance at Sep. 30, 2021	483,135	$ 5	678,358	(195,082)	(146)
Shares, Outstanding, Ending Balance at Sep. 30, 2021		51,256,553
Beginning Balance at Dec. 31, 2021	459,638	$ 5	689,275	(228,982)	(660)
Shares, Outstanding, Beginning Balance at Dec. 31, 2021		51,536,181
Issuance of Common Stock and accompanying Pre-Funded Warrants at Private Placement, net of issuance costs	149,826	$ 1	149,825
Issuance of common stock and accompanying pre-funded warrants from private placement, net of issuance costs, shares		2,769,228
Exercise of stock options	1,790		1,790
Exercise of stock options, Shares		388,061
Vesting restricted stock
Vesting restricted stock, Shares		36,866
Issuance of shares under employee stock purchase plan	256		256
Issuance of shares under employee stock purchase plan, Shares		21,093
Stock-based compensation expense	26,571		26,571
Unrealized gain (loss) on marketable securities	(5,253)				5,253
Net Loss	(119,943)			(119,943)
Ending Balance at Sep. 30, 2022	512,885	$ 6	867,717	(348,925)	(5,913)
Shares, Outstanding, Ending Balance at Sep. 30, 2022		54,751,429
Beginning Balance at Jun. 30, 2022	397,951	$ 5	707,852	(305,923)	(3,983)
Shares, Outstanding, Beginning Balance at Jun. 30, 2022		51,847,049
Issuance of Common Stock and accompanying Pre-Funded Warrants at Private Placement, net of issuance costs	149,826	$ 1	149,825
Issuance of common stock and accompanying pre-funded warrants from private placement, net of issuance costs, shares		2,769,228
Exercise of stock options	964		964
Exercise of stock options, Shares		125,534
Vesting restricted stock, Shares		9,618
Stock-based compensation expense	9,076		9,076
Unrealized gain (loss) on marketable securities	(1,930)				1,930
Net Loss	(43,002)			(43,002)
Ending Balance at Sep. 30, 2022	$ 512,885	$ 6	$ 867,717	$ (348,925)	$ (5,913)
Shares, Outstanding, Ending Balance at Sep. 30, 2022		54,751,429