Net Loss per Share (Tables)

9 Months Ended

Sep. 30, 2022

Earnings Per Share [Abstract]

Summary of Basic and Diluted Loss Per Share

Basic and diluted loss per share is computed by dividing net loss by the weighted-average common shares outstanding for the period, including the pre-funded warrants given their nominal exercise price (in thousands, except for share and per share data):

	Three Months Ended September 30,						Nine Months Ended September 30,
	2022			2021			2022			2021
Numerator:
Net loss	$	(43,002	)	$	(28,582	)	$	(119,943	)	$	(66,317	)
Denominator:
Weighted average common shares outstanding, basic and    diluted		54,535,514			50,714,846			52,600,103			46,841,636
Net loss per share, basic and diluted	$	(0.79	)	$	(0.56	)	$	(2.28	)	$	(1.42	)

Schedule of Diluted Net Loss Per Share Attributable to Common Stockholders Anti-Diluted Effect

The Company excluded the following from the computation of diluted net loss per share attributable to common stockholders at September 30, 2022 and 2021 because including them would have had an anti-dilutive effect:

	Nine Months Ended September 30,
	2022		2021
Unvested restricted stock		274,291		55,368
Options to purchase common stock		7,017,631		6,625,555
Total		7,291,922		6,680,923