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Description of Business and Summary of Significant Accounting Policies - Additional Information (Details)
1 Months Ended 12 Months Ended
Jul. 06, 2021
USD ($)
$ / shares
shares
Aug. 25, 2020
USD ($)
$ / shares
shares
Aug. 20, 2020
Jul. 31, 2021
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Description Of Business And Summary Of Significant Accounting Policies [Line Items]            
Accumulated deficit         $ 228,982,000 $ 128,765,000
Cash, cash equivalents and marketable securities         $ 567,600,000  
Reverse stock split, description         On August 20, 2020, the Board approved a 1-for-1.5949 reverse stock split of the Company’s issued and outstanding shares of common stock and a proportional adjustment to the existing conversion ratios for each of the Company’s outstanding series of preferred stock. All share and per share amounts in the accompanying consolidated financial statements and notes thereto have been retroactively adjusted for all periods presented to give effect to this reverse stock split, including reclassifying an amount equal to the reduction in par value of common stock to additional paid-in capital.  
Reverse stock split     1.5949      
Follow-on Offering            
Description Of Business And Summary Of Significant Accounting Policies [Line Items]            
Net proceeds from sale of common stock in public offering $ 257,000,000.0          
Stock Issued During Period Shares New Issues | shares 5,468,250          
Common stock per share | $ / shares $ 47.00          
Initial Public Offering            
Description Of Business And Summary Of Significant Accounting Policies [Line Items]            
Stock Issued During Period Shares New Issues | shares   9,987,520        
Common stock per share | $ / shares   $ 20.00        
Gross proceeds from issuance initial public offering   $ 199,800,000        
Underwriters            
Description Of Business And Summary Of Significant Accounting Policies [Line Items]            
Stock Issued During Period Shares New Issues | shares 713,250 1,302,720        
Private Placement | Vertex Pharmaceuticals Incorporated            
Description Of Business And Summary Of Significant Accounting Policies [Line Items]            
Aggregate proceeds from issuance of private placement $ 2,300,000 $ 13,500,000   $ 2,300    
Stock Issued During Period Shares New Issues | shares 49,928 676,354        
Common stock per share | $ / shares $ 47.00 $ 20.00