X0306 4 2020-12-21 0 0001501134 Invitae Corp NVTA 0001815185 Myers Jason W. C/O INVITAE CORPORATION 1400 16TH STREET SAN FRANCISCO CA 94103 1 0 0 1 President, Oncology Common Stock 2020-12-21 4 S 0 3232 47.0971 D 806482 D Common Stock 2020-12-21 4 S 0 3935 47.8123 D 802547 D Common Stock 2020-12-21 4 S 0 19297 49.2428 D 783250 D Common Stock 2020-12-21 4 S 0 73310 49.9499 D 709940 D Common Stock 2020-12-21 4 S 0 200 50.545 D 709740 D Common Stock 2020-12-22 4 S 0 4700 51.7264 D 705040 D Common Stock 2020-12-22 4 S 0 70942 52.8417 D 634098 D Common Stock 2020-12-22 4 S 0 42338 53.4344 D 591760 D Common Stock 2020-12-22 4 S 0 7011 54.2706 D 584749 D The sales of common stock were effected pursuant to a Rule 10b-5 sales plan adopted by the reporting person on October 1, 2020. Represents a weighted average sale price. Actual sale prices ranged from $46.50 to $47.49 per share. Reporting person undertakes to provide upon request by the Securities and Exchange Commission, the issuer or a securityholder of the issuer detailed information regarding the price and number of shares sold within the range indicated. Represents a weighted average sale price. Actual sale prices ranged from $47.52 to $48.44 per share. Represents a weighted average sale price. Actual sale prices ranged from $48.54 to $49.53 per share. Represents a weighted average sale price. Actual sale prices ranged from $49.54 to $50.53 per share. Represents a weighted average sale price. Actual sale prices ranged from $50.54 to $50.55 per share. Represents a weighted average sale price. Actual sale prices ranged from $51.08 to $52.07 per share. Represents a weighted average sale price. Actual sale prices ranged from $52.08 to $53.07 per share. Represents a weighted average sale price. Actual sale prices ranged from $53.08 to $54.07 per share. Represents a weighted average sale price. Actual sale prices ranged from $54.08 to $54.57 per share. /s/ Thomas Brida, Attorney-in-Fact 2020-12-23