X0306 4 2020-12-14 0 0001501134 Invitae Corp NVTA 0001815185 Myers Jason W. C/O INVITAE CORPORATION 1400 16TH STREET SAN FRANCISCO CA 94103 1 0 0 1 President, Oncology Common Stock 2020-12-14 4 A 0 171872 A 1211099 D Common Stock 2020-12-14 4 A 0 152527 A 1363626 D Common Stock 2020-12-16 4 S 0 71869 47.3205 D 1291757 D Common Stock 2020-12-17 4 S 0 12082 46.6375 D 1279675 D Common Stock 2020-12-17 4 S 0 33340 47.2728 D 1246335 D Common Stock 2020-12-17 4 S 0 5270 48.2328 D 1241065 D Common Stock 2020-12-17 4 G 0 300000 0.00 D 941065 D Common Stock 2020-12-18 4 S 0 81677 47.3863 D 859388 D Common Stock 2020-12-18 4 S 0 49474 48.1808 D 809914 D Common Stock 2020-12-18 4 S 0 200 48.775 D 809714 D Received in connection with the achievement of a milestone pursuant to the Agreement and Plan of Merger and Plan of Reorganization, dated as of June 21, 2020, by and among the Issuer, Apollo Merger Sub A Inc., a wholly-owned, direct subsidiary of the Issuer, Apollo Merger Sub B LLC, a wholly-owned, direct subsidiary of the Issuer, ArcherDX, Inc., and Kyle Lefkoff, solely in his capacity as holders' representative. Represents the sale of shares to cover tax withholding obligations associated with the issuance of stock. The sales of common stock were effected pursuant to a Rule 10b-5 sales plan adopted by the reporting person on October 1, 2020. Represents a weighted average sale price. Actual sale prices ranged from $45.91 to $46.90 per share. Reporting person undertakes to provide upon request by the Securities and Exchange Commission, the issuer or a securityholder of the issuer detailed information regarding the price and number of shares sold within the range indicated. Represents a weighted average sale price. Actual sale prices ranged from $46.91 to $47.90 per share. Represents a weighted average sale price. Actual sale prices ranged from $47.94 to $48.90 per share. Represents a weighted average sale price. Actual sale prices ranged from $46.74 to $47.73 per share. Represents a weighted average sale price. Actual sale prices ranged from $47.74 to $48.73 per share. Represents a weighted average sale price. Actual sale prices ranged from $48.74 to $48.81 per share. /s/ Thomas Brida, Attorney-in-Fact 2020-12-18