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Income Taxes - Schedule of Reconciliation Between Statutory Tax Rate and Effective Tax Rate (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Effective Income Tax Rate Reconciliation, Amount [Abstract]      
U.S. federal provision at statutory rate 21.00% 21.00% 21.00%
Tax credits 1.10% 1.00% 2.20%
Non-Deductible Executive Compensation (1.80%) 0.00% 0.00%
Stock-based compensation 0.10% 0.00% (0.10%)
Convertible notes (10.90%) (1.60%) 0.00%
Fair value adjustment 2.50% 2.50% 0.00%
Change in valuation allowance (11.60%) (22.80%) (22.30%)
Other (0.30%) (0.10%) (0.80%)
Effective tax rate 0.10% 0.00% 0.00%