X0508 4 2023-08-23 1 0001814140 Apexigen, Inc. APGN 0001940217 Wong Amy C/O APEXIGEN, INC. 900 INDUSTRIAL ROAD, SUITE C SAN CARLOS CA 94070 0 1 0 0 SVP, Finance and Operations 0 Common Stock 2023-08-23 4 F 0 15561 0.3851 D 66565 D Common Stock 2023-08-23 4 D 0 66565 D 0 D Employee Stock Option (right to buy) 1.27 2023-08-23 4 D 0 22333 D 2024-05-09 Common Stock 22333 0 D Employee Stock Option (right to buy) 1.47 2023-08-23 4 D 0 8708 D 2025-06-25 Common Stock 8708 0 D Employee Stock Option (right to buy) 1.66 2023-08-23 4 D 0 230507 D 2025-10-30 Common Stock 230507 0 D Employee Stock Option (right to buy) 2.25 2023-08-23 4 D 0 15367 D 2026-12-16 Common Stock 15367 0 D Employee Stock Option (right to buy) 2.25 2023-08-23 4 D 0 13830 D 2027-02-17 Common Stock 13830 0 D Employee Stock Option (right to buy) 3.62 2023-08-23 4 D 0 71159 D 2028-05-22 Common Stock 71159 0 D Employee Stock Option (right to buy) 4.59 2023-08-23 4 D 0 28685 D 2029-02-14 Common Stock 28685 0 D Employee Stock Option (right to buy) 4.59 2023-08-23 4 D 0 25611 D 2030-02-20 Common Stock 25611 0 D Employee Stock Option (right to buy) 4.59 2023-08-23 4 D 0 15366 D 2031-02-12 Common Stock 15366 0 D Employee Stock Option (right to buy) 2.46 2023-08-23 4 D 0 76800 D 2032-10-07 Common Stock 76800 0 D The shares were withheld to satisfy the reporting person's tax liability in connection with the vesting of restricted stock units. Pursuant to an Agreement and Plan of Merger, dated as of May 23, 2023 (the "Merger Agreement"), by and among the Issuer, Pyxis Oncology, Inc. ("Pyxis"), and Ascent Merger Sub Corp., at the effective time of the merger (the "Effective Time"), each share of Issuer common stock was exchanged for 0.1725 shares of Pyxis common stock and rounded down to the nearest whole share. The shares subject to the option are fully vested and immediately exercisable. Pursuant to the Merger Agreement, at the Effective Time, the option was assumed by Pyxis and converted into an option to purchase 3,852 shares of Pyxis common stock at an exercise price of $7.37 per share. The shares subject to the option are fully vested and immediately exercisable. Pursuant to the Merger Agreement, at the Effective Time, the option was assumed by Pyxis and converted into an option to purchase 1,502 shares of Pyxis common stock at an exercise price of $8.53 per share. The shares subject to the option are fully vested and immediately exercisable. Pursuant to the Merger Agreement, at the Effective Time, the option was assumed by Pyxis and converted into an option to purchase 39,761 shares of Pyxis common stock at an exercise price of $9.63 per share. The shares subject to the option are fully vested and immediately exercisable. Pursuant to the Merger Agreement, at the Effective Time, the option was assumed by Pyxis and converted into an option to purchase 2,650 shares of Pyxis common stock at an exercise price of $13.05 per share. The shares subject to the option are fully vested and immediately exercisable. Pursuant to the Merger Agreement, at the Effective Time, the option was assumed by Pyxis and converted into an option to purchase 2,385 shares of Pyxis common stock at an exercise price of $13.05 per share. The shares subject to the option are fully vested and immediately exercisable. Pursuant to the Merger Agreement, at the Effective Time, the option was assumed by Pyxis and converted into an option to purchase 12,274 shares of Pyxis common stock at an exercise price of $20.99 per share. The shares subject to the option are fully vested and immediately exercisable. Pursuant to the Merger Agreement, at the Effective Time, the option was assumed by Pyxis and converted into an option to purchase 4,947 shares of Pyxis common stock at an exercise price of $26.61 per share. The shares subject to the option vest in 48 equal monthly installments beginning on February 1, 2020. Pursuant to the Merger Agreement, at the Effective Time, the option was assumed by Pyxis and converted into an option to purchase 4,417 shares of Pyxis common stock at an exercise price of $26.61 per share. The shares subject to the option vest in 48 equal monthly installments beginning on February 1, 2021. Pursuant to the Merger Agreement, at the Effective Time, the option was assumed by Pyxis and converted into an option to purchase 2,649 shares of Pyxis common stock at an exercise price of $26.61 per share. The shares subject to the option vest in 48 equal monthly installments beginning on February 1, 2022. Pursuant to the Merger Agreement, at the Effective Time, the option was assumed by Pyxis and converted into an option to purchase 13,248 shares of Pyxis common stock at an exercise price of $14.27 per share. /s/ Francis Sarena, by power of attorney 2023-08-25