X0407 4 2023-05-23 0 0001814140 Apexigen, Inc. APGN 0001423786 Sarena Francis Willard C/O APEXIGEN, INC. 900 INDUSTRIAL ROAD, SUITE C SAN CARLOS CA 94070 0 1 0 0 President and COO 0 Common Stock 2023-05-23 4 A 0 150000 0.00 A 183084 D Common Stock 2023-05-23 4 F 0 20748 0.40 D 162336 D The reported shares are represented by restricted stock units, or RSUs. Upon signing of the merger agreement between the Issuer and Pyxis Oncology, Inc. dated May 23, 2023, 60,000 RSUs vested. The remaining 90,000 RSUs vest on the earlier of (i) the closing of the merger or (ii) September 30, 2023. The reported shares were withheld to satisfy the reporting person's tax liability in connection with the vesting of RSUs. /s/ Francis Sarena 2023-05-25