X0306 4 2021-05-19 0 0001812364 Relay Therapeutics, Inc. RLAY 0001319446 Borisy Alexis C/O RELAY THERAPEUTICS, INC. 399 BINNEY STREET, 2ND FLOOR CAMBRIDGE MA 02139 1 0 0 0 Stock Option (Right to Buy) 30.09 2021-05-19 4 A 0 16000 0.00 A 2031-05-18 Common Stock 16000 16000 D This option was granted on May 19, 2021 with respect to 16,000 shares of the Issuer's common stock and vests in full on the earlier to occur of (a) the first anniversary of the grant date or (b) the date of the next annual meeting of stockholders following the grant date. /s/ Brian Adams, as Attorney-in-Fact 2021-05-21