Leases (Tables) - 399 Binney Street [Member]

12 Months Ended

Dec. 31, 2021

Operating Leased Assets [Line Items]

Schedule of Operating Leases Presentation in Consolidated Balance Sheets

The following table summarizes the presentation of amounts recorded on the Company’s consolidated balance sheets for the operating lease at 399 Binney Street:

		December 31,
	Balance sheet location	2021		2020
Assets:
Operating lease assets	Operating lease assets	$	20,780	$	22,579
Liabilities:
Current operating lease    liabilities	Operating lease liabilities	$	1,844	$	1,521
Non-current operating lease    liabilities	Operating lease liabilities, net of current portion		21,056		22,901
	Total lease liabilities	$	22,900	$	24,422

Summary of Operating Lease Presentation in Consolidated Statements of Operations and Comprehensive Loss

The following table summarizes the effect of lease costs for the Company’s operating lease at 399 Binney Street on Company’s consolidated statements of operations and comprehensive loss for the years ended December 31, 2021, 2020 and 2019:

		Year Ended December 31,
	Statement of operations location	2021		2020		2019
Operating lease costs	Research and development	$	3,262	$	3,273	$	3,216
	General and administrative	846		748			581
	Total operating lease cost	$	4,108	$	4,021	$	3,797

Summary of Future Minimum Lease Payments

The minimum lease payments for the Company’s operating lease at 399 Binney Street as of December 31, 2021 for the next five years and thereafter is expected to be as follows:

Year Ending December 31,	Amount
2022		4,134
2023		4,254
2024		4,377
2025		4,503
2026		4,634
Thereafter		11,325
Total lease payments		33,227
Less: interest		(10,327	)
Present value of operating lease liabilities	$	22,900