X0206 3 2021-12-17 0 0001812364 Relay Therapeutics, Inc. RLAY 0001899340 Porter Andy C/O RELAY THERAPEUTICS, INC. 399 BINNEY STREET CAMBRIDGE MA 02139 0 1 0 0 See Remarks Common Stock 23407 D Stock Option (Right to Buy) 5.042 2029-10-09 Common Stock 143926 D Stock Option (Right to Buy) 5.22 2030-03-01 Common Stock 13861 D Stock Option (Right to Buy) 5.22 2030-03-01 Common Stock 47522 D Stock Option (Right to Buy) 34.25 2031-03-25 Common Stock 28000 D Includes 12,250 restricted stock units ("RSUs") granted to the reporting person pursuant to the Issuer's 2020 Stock Option and Incentive Plan. Each RSU represents a contingent right to receive one share of the Issuer's common stock upon vesting. The RSUs commenced vesting in 16 equal quarterly installments following the grant date of March 26, 2021, subject to the reporting person's continued service with the Issuer through each vesting date. 24,239 shares underlying this option have vested and the remainder shall vest in equal quarterly installments from January 21, 2022 to October 21, 2023, subject to the reporting person's continued service with the Issuer through each vesting date. 2,970 shares underlying this option have vested and the remainder shall vest in equal quarterly installments from December 23, 2021 to June 23, 2024, subject to the reporting person's continued service with the Issuer through each vesting date. 11,880 shares underlying this option have vested and the remainder shall vest in equal quarterly installments from March 11, 2022 to December 11, 2024, subject to the reporting person's continued service with the Issuer through each vesting date. 3,500 shares underlying this option have vested and the remainder shall vest in equal quarterly installments from December 26, 2021 to March 26, 2025, subject to the reporting person's continued service with the Issuer through each vesting date. Title: Executive Vice President, Chief People Experience Officer Exhibit 24 - Power of Attorney /s/ Brian Adams, as Attorney-in-Fact 2021-12-27