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Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Cash flows from operating activities:    
Net loss $ (518,494) $ (62,015)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 22,086 15,791
Depreciation and amortization 464 167
Non-cash lease expense (109) (38)
Change in fair value of warrant liability (209) (260)
Amortization of premium on marketable securities (7,346) (8,798)
Realized loss on marketable securities 17 183
Net loss on disposal of property and equipment 171 19
Acquired in-process research and development 425,070 0
Change in operating assets and liabilities:    
Accounts receivable (112) 0
Prepaid expenses and other current assets (7,336) 843
Interest receivable on marketable securities (437) (548)
Other non-current assets 104 (587)
Accounts payable 4,378 234
Contract liabilities (1,868) 0
Accrued expenses (490) 2,039
Net cash used in operating activities (84,111) (52,970)
Cash flow from investing activities:    
Cash acquired from AnHeart acquisition 19,863 0
Transaction costs related to AnHeart acquisition (7,343) 0
Purchases of marketable securities (307,603) (554,635)
Proceeds from sale of marketable securities 366,189 530,449
Purchases of property and equipment (175) (56)
Net cash provided by (used in) investing activities 70,931 (24,242)
Cash flow from financing activities:    
Proceeds from borrowings 7,035 0
Payments on borrowings (9,530) 0
Proceeds from issuance of Common Stock under ESPP 108 133
Proceeds from exercises of options 3,618 375
Net cash provided by financing activities 1,231 508
Effect of foreign exchange rate changes on cash and cash equivalents (664) 0
Net decrease in cash and cash equivalents (12,613) (76,704)
Cash and cash equivalents, beginning of the period 42,649 101,099
Cash and cash equivalents, end of the period 30,036 24,395
Non-cash investing activities:    
Issuance of Common Stock related to the AnHeart acquisition 89,297 0
Issuance of convertible preferred stock related to the AnHeart acquisition 274,938 0
Issuance of warrants related to the AnHeart acquisition 764 0
Issuance of replacement awards related to the AnHeart acquisition 24,818 0
Non-cash operating activities:    
Right-of-use asset recognized 213 1,216
Operating lease liability recognized $ 213 $ 1,216