Fair Value Measurements and Marketable Securities Available For Sale - Schedule of Cost, Aggregate Fair Value and Unrealized Gains of Marketable Securities Available-for-sale (Details) - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Amortized Cost	$ 663,233	$ 719,028
Unrealized Gains	15	363
Unrealized Losses	(8,132)	(1,714)
Fair Value	655,116	717,677
Marketable securities [Member]
Amortized Cost	543,377	634,320
Unrealized Gains	4	363
Unrealized Losses	(8,126)	(1,714)
Fair Value	535,255	632,969
Cash Equivalents [Member]
Amortized Cost	119,856	84,708
Unrealized Gains	11	0
Unrealized Losses	(6)	0
Fair Value	119,861	84,708
Money Market Funds [Member] | Cash Equivalents [Member]
Amortized Cost	59,991	53,292
Unrealized Gains	0	0
Unrealized Losses	0	0
Fair Value	59,991	53,292
Certificate of deposits [Member] | Marketable securities [Member]
Amortized Cost	6,137	3,000
Unrealized Gains	2	0
Unrealized Losses	(41)	0
Fair Value	6,098	3,000
Commercial Paper [Member] | Marketable securities [Member]
Amortized Cost	31,776	16,889
Unrealized Gains	0	3
Unrealized Losses	(166)	0
Fair Value	31,610	16,892
Commercial Paper [Member] | Cash Equivalents [Member]
Amortized Cost	4,885	30,845
Unrealized Gains	0	0
Unrealized Losses	(1)	0
Fair Value	4,884	30,845
U.S. Government Securities [Member] | Cash Equivalents [Member]
Amortized Cost	48,771
Unrealized Gains	11
Unrealized Losses	0
Fair Value	48,782
U.S. Government And Government Agency Securities [Member] | Marketable securities [Member]
Amortized Cost	271,300	267,792
Unrealized Gains	1	213
Unrealized Losses	(3,816)	(738)
Fair Value	267,485	267,267
Corporate Bonds [Member] | Marketable securities [Member]
Amortized Cost	230,600	320,827
Unrealized Gains	1	147
Unrealized Losses	(4,046)	(782)
Fair Value	226,555	320,192
Corporate Bonds [Member] | Cash Equivalents [Member]
Amortized Cost	6,209	571
Unrealized Gains	0	0
Unrealized Losses	(5)	0
Fair Value	6,204	571
Municipal Bonds [Member] | Marketable securities [Member]
Amortized Cost	3,564	10,849
Unrealized Gains	0	0
Unrealized Losses	(57)	(28)
Fair Value	$ 3,507	10,821
Exchange Traded Funds [Member] | Marketable securities [Member]
Amortized Cost		14,963
Unrealized Gains		0
Unrealized Losses		(166)
Fair Value		$ 14,797