Stock-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2022

Share-Based Payment Arrangement [Abstract]

Summary of Stock-Based Compensation Expense

The stock-based compensation expense included in the Company’s consolidated statement of operations and comprehensive loss for the three and nine months ended September 30, 2022 and 2021 is as follows (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2022		2021		2022		2021
Research and development	$	353	$	1,667	$	4,089	$	3,749
General and administrative		2,587		1,082		7,215		2,719
	$	2,940	$	2,749	$	11,304	$	6,468

Summary of Stock Option Activity under 2019 Plan and 2021 Plan

The following table summarizes stock option activity under the 2019 Plan and the 2021 Plan for the nine months ended September 30, 2022.

	Shares
Outstanding at December 31, 2021		11,216,275
Granted		17,743,771
Exercised		(360,760	)
Forfeited or canceled		(5,200,692	)
Outstanding at September 30, 2022		23,398,594
Exercisable at September 30, 2022		3,037,600