Fair Value Measurements and Marketable Securities Available For Sale - Schedule of Cost, Aggregate Fair Value and Unrealized Gains of Marketable Securities Available-for-sale (Details) - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Amortized Cost	$ 678,136	$ 719,028
Unrealized Gains	57	363
Unrealized Losses	(7,035)	(1,714)
Fair Value	671,158	717,677
Cash Equivalents [Member]
Amortized Cost	69,694	84,708
Unrealized Gains	0	0
Unrealized Losses	(12)	0
Fair Value	69,682	84,708
Marketable securities [Member]
Amortized Cost	608,442	634,320
Unrealized Gains	57	363
Unrealized Losses	(7,023)	(1,714)
Fair Value	601,476	632,969
Money Market Funds [Member] | Cash Equivalents [Member]
Amortized Cost	20,998	53,292
Unrealized Gains	0	0
Unrealized Losses	0	0
Fair Value	20,998	53,292
Certificate of deposits [Member] | Marketable securities [Member]
Amortized Cost	5,338	3,000
Unrealized Gains	0
Unrealized Losses	(50)	0
Fair Value	5,288	3,000
Commercial Paper [Member] | Cash Equivalents [Member]
Amortized Cost	5,466	30,845
Unrealized Gains	0	0
Unrealized Losses	0	0
Fair Value	5,466	30,845
Commercial Paper [Member] | Marketable securities [Member]
Amortized Cost	38,947	16,889
Unrealized Gains	5	3
Unrealized Losses	(181)	0
Fair Value	38,771	16,892
U.S. Government Securities [Member] | Cash Equivalents [Member]
Amortized Cost	43,230
Unrealized Gains	0
Unrealized Losses	(12)
Fair Value	43,218
U.S. Government And Government Agency Securities [Member] | Marketable securities [Member]
Amortized Cost	285,175	267,792
Unrealized Gains	15	213
Unrealized Losses	(2,930)	(738)
Fair Value	282,260	267,267
Corporate Bonds [Member] | Cash Equivalents [Member]
Amortized Cost		571
Unrealized Gains		0
Unrealized Losses		0
Fair Value		571
Corporate Bonds [Member] | Marketable securities [Member]
Amortized Cost	269,657	320,827
Unrealized Gains	37	147
Unrealized Losses	(3,793)	(782)
Fair Value	265,901	320,192
Municipal Bonds [Member] | Marketable securities [Member]
Amortized Cost	9,325	10,849
Unrealized Gains	0	0
Unrealized Losses	(69)	(28)
Fair Value	$ 9,256	10,821
Exchange Traded Funds [Member] | Marketable securities [Member]
Amortized Cost		14,963
Unrealized Gains		0
Unrealized Losses		(166)
Fair Value		$ 14,797