Fair Value Measurements and Marketable Securities Available For Sale - Schedule of Cost, Aggregate Fair Value and Unrealized Gains of Marketable Securities Available-for-sale (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Amortized Cost	$ 688,895	$ 719,028
Unrealized Gains	82	363
Unrealized Losses	(6,299)	(1,714)
Fair Value	682,678	717,677
Cash Equivalents [Member]
Amortized Cost	51,179	84,708
Unrealized Gains	3	0
Unrealized Losses	0	0
Fair Value	51,182	84,708
Marketable securities [Member]
Amortized Cost	637,716	634,320
Unrealized Gains	79	363
Unrealized Losses	(6,299)	(1,714)
Fair Value	631,496	632,969
Money Market Funds [Member] | Cash Equivalents [Member]
Amortized Cost	39,188	53,292
Unrealized Gains	0	0
Unrealized Losses	0	0
Fair Value	39,188	53,292
Certificate of deposits [Member] | Marketable securities [Member]
Amortized Cost	8,338	3,000
Unrealized Gains	2
Unrealized Losses	(36)	0
Fair Value	8,304	3,000
Commercial Paper [Member] | Cash Equivalents [Member]
Amortized Cost	5,994	30,845
Unrealized Gains	2	0
Unrealized Losses	0	0
Fair Value	5,996	30,845
Commercial Paper [Member] | Marketable securities [Member]
Amortized Cost	34,674	16,889
Unrealized Gains	0	3
Unrealized Losses	(131)	0
Fair Value	34,543	16,892
U.S. Government Securities [Member] | Cash Equivalents [Member]
Amortized Cost	5,997
Unrealized Gains	1
Unrealized Losses	0
Fair Value	5,998
U.S. Government And Government Agency Securities [Member] | Marketable securities [Member]
Amortized Cost	295,251	267,792
Unrealized Gains	56	213
Unrealized Losses	(2,629)	(738)
Fair Value	292,678	267,267
Corporate Bonds [Member] | Cash Equivalents [Member]
Amortized Cost		571
Unrealized Gains		0
Unrealized Losses		0
Fair Value		571
Corporate Bonds [Member] | Marketable securities [Member]
Amortized Cost	289,115	320,827
Unrealized Gains	21	147
Unrealized Losses	(3,432)	(782)
Fair Value	285,704	320,192
Municipal Bonds [Member] | Marketable securities [Member]
Amortized Cost	10,338	10,849
Unrealized Gains	0	0
Unrealized Losses	(71)	(28)
Fair Value	$ 10,267	10,821
Exchange Traded Funds [Member] | Marketable securities [Member]
Amortized Cost		14,963
Unrealized Gains		0
Unrealized Losses		(166)
Fair Value		$ 14,797