Consolidated Statement of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Cash Flows from Operating Activities:
Net loss	$ (86,848)	$ (41,659)
Adjustments to reconcile net loss to net cash used in operating activities:
Issuance of common stock	3,787	135,657	[1]
Stock-based compensation	9,268	2,202
Depreciation and amortization	184	103
Non-cash lease expense	184
Change in fair value of warrant liability	(4,231)	0
Net amortization on marketable securities	(4,593)	(933)
Net loss (gain) on marketable securities	80	(218)
Change in operating assets and liabilities (net of assets and liabilities acquired in the Merger)
Prepaid expenses and other current assets	(2,416)	(727)
Interest receivable on marketable securities	(1,947)	(264)
Accounts payable	1,861	34
Accrued expenses	7,452	2,921
Deferred rent	(157)	146
Net cash used in operating activities	(68,190)	(36,529)
Cash Flows from Investing Activities:
Purchases of marketable securities	(609,300)	(143,289)
Proceeds from sale of marketable securities	154,913	70,606
Proceeds from investment held to maturity		2,508
Purchases of property and equipment	(282)	(145)
Net cash (used in) provided by investing activities	(454,669)	(70,320)
Cash Flows from Financing Activities:
Proceeds from the Merger, net of offering costs paid (see Note 3)	624,769
Proceeds from issuance of stock, net of issuance costs		135,657
Proceeds from issuance of common stock under ESPP	308
Proceeds from exercises of options	450
Deferred financing costs		(2,522)
Net cash provided by financing activities	625,527	133,135
Net increase in cash and cash equivalents	102,668	26,286
Cash and cash equivalents, beginning of the period	29,755	3,469
Cash and cash equivalents, end of the period	132,423	29,755
Non-cash operating activity:
Right-of-use asset obtained in exchange for operating lease liability	3,917
Non-cash investing and financing activity:
Issuance of common stock for in-process research and development	3,787
Deferred financing costs in accounts payable and accrued expenses	$ 0	$ 403

[1] Reflected net of deemed dividend and beneficial conversion feature (see note 8)