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                          June 6, 2022

       James Rolke
       Chief Executive Officer
       Revelation Biosciences, Inc.
       4660 La Jolla Village Drive, Suite 100
       San Diego, California 92122

                                                        Re: Revelation
Biosciences, Inc.
                                                            Registration
Statement on Form S-1
                                                            Filed May 31, 2022
                                                            File No. 333-265326

       Dear Mr. Rolke:

              This is to advise you that we have not reviewed and will not
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Chris
Edwards at 202-551-6761 with any questions.




                          Sincerely,


                          Division of Corporation Finance

                          Office of Life Sciences
       cc:                                              J.P. Galda, Esq.