X0306 4 2021-11-22 0 0001810182 ALX ONCOLOGY HOLDINGS INC ALXO 0001817127 Randolph Sophia C/O ALX ONCOLOGY HOLDINGS INC. 866 MALCOLM ROAD, SUITE 100 BURLINGAME CA 94010 1 1 0 0 Chief Medical Officer Common Stock 2021-11-22 4 M 0 30000 4.08 A 179428 D Common Stock 2021-11-22 4 S 0 14884 36.772 D 164544 D Stock Option (right to buy) 4.08 2021-11-22 4 M 0 30000 0.00 D 2030-03-09 Common Stock 30000 107906 D The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $36.54 to $37.10, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price. The option is subject to an early exercise provision and is immediately exercisable. Shares subject to the option vest in 48 equal monthly installments beginning on April 9, 2020. /s/ Peter Garcia, by power of attorney 2021-11-23