Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021
Operating activities
Net loss	$ (92,773)	$ (55,025)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	237	17
Non-cash lease costs	816	460
Stock-based compensation	17,544	8,228
Net amortization of premiums and accretion of discounts on investments	(256)
Changes in operating assets and liabilities
Prepaid expenses and other current assets	(2,613)	(2,042)
Other assets	(267)	(10,653)
Accounts payable	2,052	3,620
Payable and accrued liabilities due to related party	1,129	386
Accrued expenses and other current liabilities	6,412	2,333
Other non-current liabilities	(836)	2,063
Net cash used in operating activities	(68,555)	(50,613)
Investing activities
Purchase of investments	(315,820)
Maturities of investments	70,500
Purchase of property and equipment	(1,038)	(405)
Net cash used in investing activities	(246,358)	(405)
Financing activities
Proceeds from exercise of stock options under equity incentive plan	345	2,022
Proceeds from issuance of common stock under employee stock purchase plan	302	103
Principal payments on finance leases	(281)	(177)
Net cash provided by financing activities	366	1,948
Net decrease in cash, cash equivalents and restricted cash	(314,547)	(49,070)
Cash, cash equivalents and restricted cash at beginning of year	363,667	434,219
Cash, cash equivalents and restricted cash at end of period	49,120	385,149
Supplemental disclosure of non-cash investing and financing activities
Purchase of property and equipment in accounts payable and accrued expenses	876	129
Right-of-use asset acquired under operating leases	4,684	1,812
Right-of-use asset acquired under finance leases		834
Reconciliation of cash and cash equivalents and restricted cash:
Cash and cash equivalents	49,054	385,149
Restricted cash (included in other assets)	66
Total cash and cash equivalents and restricted cash	$ 49,120	$ 385,149