144 0001809613 XXXXXXXX LIVE 0001811623 PaxMedica, Inc. 001-41475 303 SOUTH BROADWAY, SUITE 125 TARRYTOWN NY 10591 914-987-2876 Derby Michael Officer Executive Chairman Common Stock Georgeson Securities Corp

144 Fernwood Avenue Edison NJ 08837

13540 6620.00 16436509 08/28/2023 NASDAQ Common Stock 08/28/2023 Restricted Stock Vesting Paxmedica, Inc. N 40000 08/28/2023 Services Rendered Y Date of sale includes sales done on 8/28/23 & 8/29/23. 08/30/2023 Conformed Signature on File