144 0001808968 XXXXXXXX LIVE 0001285550 ClearPoint Neuro, Inc. 001-34822 120 S. Sierra Ave Suite Solana Beach CA 92075 888-287-9109 MATTHEW B KLEIN Director Common Morgan Stanley Smith Barney LLC Executive Financial Services

1 New York Plaza 8th Floor New York NY 10004

16000 185392.00 29990000 05/21/2026 NASDAQ Common 05/16/2025 Restricted stock vesting under a registered plan Issuer N 16000 05/16/2025 Compensation Y 05/21/2026 /s/ Matthew Klein