Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023
Cash flows from operating activities
Net loss	$ (45,344)	$ (49,851)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	614	447
Stock-based compensation	15,325	12,771
Non-cash: Net accretion of available-for-sale debt securities	(5,527)	(5,386)
Change in operating lease right-of-use assets	(5)	0
Changes in operating assets and liabilities:
Grants receivable	(397)	584
Research and development tax credits receivable	(1,705)	(729)
Refundable income taxes	140	(1,839)
Unbilled milestone receivable	(35,000)
Prepaid expenses and other current assets	(1,051)	702
Accounts payable	(218)	(2,512)
Accrued expenses and other liabilities	5,130	989
Income tax payable	0	0
Deferred income	(399)	1,318
Deferred revenue	0	(12,595)
Unrecognized tax benefits	2,110	0
Net cash used in operating activities	(66,327)	(56,101)
Cash flows from investing activities
Purchases of investments	(245,073)	(139,037)
Proceeds from maturities of investments	193,182	128,265
Purchase of property and equipment	(1,387)	(819)
Net cash used in investing activities	(53,278)	(11,591)
Cash flows from financing activities
Proceeds from issuance of common stock upon exercise of options and ESPP purchases	2,404	796
Proceeds from issuance of common stock and pre funded warrants	119,994
Net cash provided by financing activities	122,398	796
Effects of exchange rate changes on cash, cash equivalents and restricted cash	(2,843)	(1,659)
Net decrease in cash, cash equivalents and restricted cash	(50)	(68,555)
Cash, cash equivalents and restricted cash at beginning of period	251,451	285,038
Cash, cash equivalents and restricted cash at end of period	251,401	216,483
Non-cash investing and financing activities
Capital expenditure included in accounts payable	2	20
Operating lease liabilities arising from obtaining right-of-use assets	235	1,059
Unrealized loss on available-for-sale securities	(906)	(1,620)
Offering costs included within accounts payable	277	0
Supplemental disclosure of cash flows
Cash paid for taxes	$ 2,384	$ 4,321