Commitments and Contingencies - Additional Information (Details)	1 Months Ended	3 Months Ended		9 Months Ended	12 Months Ended
	Jan. 31, 2021	Mar. 31, 2022 USD ($) m² ft²	Mar. 31, 2021 USD ($)	Sep. 30, 2021	Dec. 31, 2021 USD ($)	Nov. 30, 2021 USD ($)	Mar. 31, 2019 USD ($)
Other Commitments [Line Items]
Land subject to leases | m²		1,577
Operating leases, rent expense		$ 300,000	$ 200,000
Extension of office lease		In January 2021, the Company entered into an amendment to extend the lease, effective February 2021 with a termination date of January 2030, and increase the office and laboratory space
Wu Xi Agreement
Other Commitments [Line Items]
Minimum commitments		$ 0			$ 0
Payments for Royalties		0			0
Gosselies, Belgium
Other Commitments [Line Items]
Operating lease, Hand serving to secure lease obligation		$ 97,000,000			99,000
Cambridge, Massachusetts
Other Commitments [Line Items]
Land subject to leases | ft²		2,479
Lease expiration date		May 31, 2022
Operating lease, Letter of credit to secure lease obligation							$ 57,000
Watertown Massachusetts [Member]
Other Commitments [Line Items]
Land subject to leases | ft²		9,068
Operating lease, Letter of credit to secure lease obligation						$ 142,000
Office and Laboratory Space | Gosselies, Belgium
Other Commitments [Line Items]
Lease commencement date	Feb. 28, 2021	May 31, 2016
Lease expiration date	Jan. 31, 2030	Dec. 31, 2021
Lessee, operating lease, existence of option to extend [true false]				true
Office and Laboratory Space | Gosselies, Belgium | AmendmentToExtendLeaseMember
Other Commitments [Line Items]
Increase land subject to leases | m²		201
Office and Laboratory Space | Gosselies, Belgium | Agreement To Extend Lease Member
Other Commitments [Line Items]
Increase land subject to leases | ft²		453
Office | Cambridge, Massachusetts
Other Commitments [Line Items]
Lease commencement date		May 31, 2019
Lease expiration date		Feb. 28, 2027
Office | Watertown Massachusetts [Member]
Other Commitments [Line Items]
Lease commencement date		Nov. 30, 2021
Contract Termination
Other Commitments [Line Items]
Restructuring charges		$ 0			$ 0
Minimum
Other Commitments [Line Items]
Contractual Agreement Cancelation Notice period		30 days
Average car lease duration		48 months
Maximum
Other Commitments [Line Items]
Contractual Agreement Cancelation Notice period		60 days
Average car lease duration		60 months