Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Cash flows from operating activities
Net loss	$ 214,521	$ (38,033)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	603	535
Stock-based compensation	13,794	4,292
Change in operating lease right of use assets	12
Fair value adjustment for preferred stock tranche rights liability		(1,265)
Deferred rent		(35)
Changes in operating assets and liabilities:
Grants receivable	(4,071)	5,175
Research and development tax credits receivable	727	(142)
Refundable income taxes	(7,544)
Prepaid expenses and other current assets	(11,789)	(1,927)
Accounts payable	2,280	1,677
Accrued expenses and other liabilities	9,959	2,759
Deferred income	3,480	0
Deferred revenue	281,128	1,788
Unrecognized tax benefits	17,000	0
Net cash provided by (used in) operating activities	513,140	(25,176)
Cash flows from investing activities
Purchase of property and equipment	(1,181)	(356)
Purchase other assets	(61)	(21)
Net cash used in investing activities	(1,242)	(377)
Cash flows from financing activities
Proceeds from issuance of Preferred Stock		125,358
Payment of issuance costs on Series B-2 Preferred Stock		(332)
Proceeds from issuance of common stock upon exercise of options	2,943	655
Proceeds from grants repayable	716	4,046
Net cash provided by financing activities	3,659	340,339
Effects of exchange rate changes on cash, cash equivalents and restricted cash	(3,176)	1,678
Net increase (decrease) in cash, cash equivalents and restricted cash	512,381	316,464
Cash, cash equivalents and restricted cash at beginning of year	336,454	19,990
Cash, cash equivalents and restricted cash at end of year	848,835	336,454
Non-cash investing and financing activities
Conversion of redeemable convertible preferred stock to common stock upon closing of the initial public offering		181,903
Capital expenditure included in accounts payable	175
Accretion of Series B and B-2 Preferred Stock to redemption value		5,120
Settlement of preferred stock tranche right		4,135
Operating lease liabilities arising from obtaining right-of-use assets (non-cash)	5,877
Supplemental disclosure of cash flows
Cash paid for taxes	$ 32,019	108
Series B-2 Preferred Stock
Cash flows from financing activities
Proceeds from initial public offering, net of underwriting discount		213,660
Payment of initial public offering costs		$ (3,048)