Summary of significant accounting policies - Summary of Property and Equipment Estimated Useful Lives (Details)	12 Months Ended
	Dec. 31, 2021
Property Plant And Equipment [Line Items]
Leasehold improvements	Shorter of useful life or term of lease
Computer equipment and software
Property Plant And Equipment [Line Items]
Useful life (in years)	3 years
Furniture, fixtures and other
Property Plant And Equipment [Line Items]
Useful life (in years)	5 years
Scientific equipment | Minimum
Property Plant And Equipment [Line Items]
Useful life (in years)	5 years
Scientific equipment | Maximum
Property Plant And Equipment [Line Items]
Useful life (in years)	6 years