<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2021-02-26</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000029669</issuerCik>
        <issuerName>RR Donnelley &amp; Sons Co</issuerName>
        <issuerTradingSymbol>RRD</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001808166</rptOwnerCik>
            <rptOwnerName>Ray James R Jr</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O R.R. DONNELLEY &amp; SONS COMPANY</rptOwnerStreet1>
            <rptOwnerStreet2>35 W. WACKER DRIVE</rptOwnerStreet2>
            <rptOwnerCity>CHICAGO</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60601</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>No Securities Owned</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes></footnotes>

    <remarks>James Ray, Jr. became a director of R.R. Donnelley &amp; Sons Company on February 26, 2021. Exhibit Index Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Deborah L. Steiner, Attorney-in-Fact for James Ray, Jr.</signatureName>
        <signatureDate>2021-03-02</signatureDate>
    </ownerSignature>
</ownershipDocument>
