Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022
Revenue:
Collaboration agreements	$ 2,159	$ 112,545	$ 38,086	$ 113,632
Operating expenses:
Research and development, net of tax credits	32,709	31,242	98,327	89,175
General and administrative	7,868	7,904	25,116	24,621
Total operating expenses	40,577	39,146	123,443	113,796
(Loss) income from operations	(38,418)	73,399	(85,357)	(164)
Other income (expense), net
Realized and unrealized (loss) gain on foreign exchange	(40)	126	(137)	250
Interest income	3,312	2,027	10,228	2,700
Other expense	(32)	(37)	(73)	(56)
Total other income, net	3,240	2,116	10,018	2,894
(Loss) income before income taxes	(35,178)	75,515	(75,339)	2,730
Income tax recovery (expense)	16,299	(54)	9,573	(119)
Net (loss) income	(18,879)	75,461	(65,766)	2,611
Unrealized gain (loss) on available-for-sale marketable securities	172	(524)	176	(524)
Total other comprehensive gain (loss)	172	(524)	176	(524)
Comprehensive (loss) income	$ (18,707)	$ 74,937	$ (65,590)	$ 2,087
Net (loss) income per share attributable to common shareholders--basic	$ (0.45)	$ 1.8	$ (1.56)	$ 0.06
Net (loss) income per share attributable to common shareholders--diluted	$ (0.45)	$ 1.71	$ (1.56)	$ 0.06
Weighted-average common shares outstanding-basic	42,102,685	41,945,617	42,077,857	41,902,554
Weighted-average common shares outstanding-diluted	42,102,685	44,177,376	42,077,857	44,160,481