Collaborations - Schedule of Transaction Price Performance Obligations (Details) $ in Thousands	Dec. 31, 2022 USD ($)
Bristol-Myers Squibb Company
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Transaction price	$ 50,000
Hoffmann La Roche Inc And F Hoffmann La Roche Ltd
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Transaction price	134,626
Research Activities | Bristol-Myers Squibb Company
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Transaction price	6,405
Options to License Druggable Targets | Bristol-Myers Squibb Company
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Transaction price	31,148
Options to License Undruggable Targets | Bristol-Myers Squibb Company
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Transaction price	12,447
Combined Licenses | Hoffmann La Roche Inc And F Hoffmann La Roche Ltd
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Transaction price	105,327
Completion of Continuing Trials | Hoffmann La Roche Inc And F Hoffmann La Roche Ltd
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Transaction price	26,585
Transfer of Clinical Trial Materials | Hoffmann La Roche Inc And F Hoffmann La Roche Ltd
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Transaction price	$ 2,714