Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 159,521	$ 334,427
Marketable securities	184,420	7,439
Research and development tax credits receivable	1,280	2,580
Collaboration revenue receivable	1,525	0
Other receivables	1,518	654
Prepaid expenses	5,715	6,314
Total current assets	353,979	351,414
Property and equipment, net	4,228	5,604
Operating lease right-of-use assets	5,371	7,491
Other assets	497	586
Deferred tax assets	0	3,620
TOTAL ASSETS	364,075	368,715
Current liabilities:
Accounts payable	461	2,302
Accrued expenses and other current liabilities	21,645	18,622
Operating lease liabilities, current portion	2,171	1,721
Deferred revenue, current portion	53,102	11,921
Income tax payable	1,240	523
Total current liabilities	78,619	35,089
Operating lease liabilities, net of current portion	3,257	5,592
Deferred revenue, net of current portion	2,682	39,613
TOTAL LIABILITIES	84,558	80,294
Commitments and Contingencies
SHAREHOLDERS' EQUITY:
Preferred shares, no par value per share; unlimited shares authorized as of December 31, 2022 and December 31, 2021, respectively; 0 shares issued and outstanding as of December 31, 2022, and December 31, 2021, respectively	0	0
Common shares, no par value per share; unlimited shares authorized as of December 31, 2022 and December 31, 2021; 42,036,193 and 41,850,162 shares issued and outstanding as of December 31, 2022 and December 31, 2021, respectively	482,032	480,699
Additional paid-in capital	37,226	17,988
Accumulated other comprehensive loss	(428)	0
Accumulated deficit	(239,313)	(210,266)
TOTAL SHAREHOLDERS' EQUITY	279,517	288,421
TOTAL LIABILITIES AND SHAREHOLDERS' EQUITY	$ 364,075	$ 368,715