Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	3 Months Ended
Mar. 31, 2022	Mar. 31, 2021
Cash Flows From Operating Activities:
Net loss and comprehensive loss for the period	$ (34,757)	$ (21,417)
Adjustments to reconcile net loss to net cash used in operating activities:
Share-based compensation expense	4,755	2,057
Depreciation expense	516	322
Non-cash lease expense	544	371
Foreign exchange gain	(40)	(41)
Amortization of premiums on marketable securities	21	29
Deferred tax	(1,315)	(174)
Changes in operating assets and liabilities:
Prepaid expenses	2,399	2,796
Research and development tax credits receivable	(399)	(238)
Other receivables	(5)	1,017
Accounts payable	(772)	1,201
Accrued expenses and other current liabilities	(1,487)	253
Operating lease liability, current portion	153	(135)
Income tax payable	1,347	12
Operating lease liability, net of current portion	(558)	(114)
Deferred revenue	(408)	(166)
Net cash used in operating activities	(30,006)	(14,227)
Cash Flows From Investing Activities:
Purchases of property and equipment	(487)	(772)
Proceeds from maturities of marketable securities	2,650
Purchase of marketable securities	(1,760)
Net cash provided by (used in) investing activities	403	(772)
Cash Flows From Financing Activities:
Proceeds from exercise of stock options	28	183
Proceeds from issuance of common stock under the 2020 Employee Share Purchase Plan	213
Net cash provided by financing activities	241	183
Effect of exchange rate fluctuations on cash held	71	34
Net (Decrease) Increase In Cash And Cash Equivalents And Restricted Cash	(29,291)	(14,782)
Cash and cash equivalents and restricted cash at beginning of period	334,427	326,396
Cash and cash equivalents and restricted cash at end of period	305,136	311,614
Reconciliation Of Cash And Cash Equivalents And Restricted Cash
Cash and cash equivalents	305,136	311,399
Restricted cash		215
Total cash and cash equivalents and restricted cash	305,136	311,614
Supplemental Disclosure Of Cash Flow Information:
Property and equipment purchases incurred but not yet paid	1,541	286
Right-of-use asset obtained in exchange for new operating lease liability	$ 56	$ 0

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