X0306 4 2020-12-02 0 0001807901 Pandion Therapeutics, Inc. PAND 0001617541 Dorton Katina C/O PANDION THERAPEUTICS, INC., 134 COOLIDGE AVENUE WATERTOWN MA 02472 1 0 0 0 Stock Option (right to buy) 16.96 2020-12-02 4 A 0 27994 0.00 A 2030-12-01 Common Stock 27994 27994 D This option award was granted on December 2, 2020. The shares underlying the award vest in equal monthly installments following December 2, 2020 through December 2, 2023, subject to the reporting person's continued service on each applicable vesting date. /s/ Edward D. Freedman, as attorney-in-fact for Katina Dorton 2020-12-04