<?xml version="1.0" ?>
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  <proxyTable>
    <issuerName>WAVE LIFE SCIENCES LTD.</issuerName>
    <cusip>Y95308105</cusip>
    <isin>SG9999014716</isin>
    <figi></figi>
    <meetingDate>08/01/2023</meetingDate>
    <voteDescription>To approve, by a non-binding advisory vote, the compensation of our named executive officers as disclosed in the proxy statement</voteDescription>
    <voteCategories>
      <voteCategory>
        <categoryType>SECTION 14A SAY-ON-PAY VOTES</categoryType>
      </voteCategory>
    </voteCategories>
    <voteSource>ISSUER</voteSource>
    <sharesVoted>7019255</sharesVoted>
    <sharesOnLoan>0</sharesOnLoan>
    <vote>
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        <howVoted>FOR</howVoted>
        <sharesVoted>7019255</sharesVoted>
        <managementRecommendation>FOR</managementRecommendation>
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    </vote>
    <voteSeries></voteSeries>
    <voteOtherInfo></voteOtherInfo>
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  <proxyTable>
    <issuerName>ARROWHEAD PHARMACEUTICALS, INC.</issuerName>
    <cusip>04280A100</cusip>
    <isin>US04280A1007</isin>
    <figi></figi>
    <meetingDate>03/14/2024</meetingDate>
    <voteDescription>Advisory Vote to Approve Executive Compensation.</voteDescription>
    <voteCategories>
      <voteCategory>
        <categoryType>SECTION 14A SAY-ON-PAY VOTES</categoryType>
      </voteCategory>
    </voteCategories>
    <voteSource>ISSUER</voteSource>
    <sharesVoted>67400</sharesVoted>
    <sharesOnLoan>0</sharesOnLoan>
    <vote>
      <voteRecord>
        <howVoted>FOR</howVoted>
        <sharesVoted>67400</sharesVoted>
        <managementRecommendation>FOR</managementRecommendation>
      </voteRecord>
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    <voteSeries></voteSeries>
    <voteOtherInfo></voteOtherInfo>
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  <proxyTable>
    <issuerName>SPRINGWORKS THERAPEUTICS INC</issuerName>
    <cusip>85205L107</cusip>
    <isin>US85205L1070</isin>
    <figi></figi>
    <meetingDate>05/16/2024</meetingDate>
    <voteDescription>Non-binding advisory vote on executive compensation</voteDescription>
    <voteCategories>
      <voteCategory>
        <categoryType>SECTION 14A SAY-ON-PAY VOTES</categoryType>
      </voteCategory>
    </voteCategories>
    <otherVoteDescription></otherVoteDescription>
    <voteSource>ISSUER</voteSource>
    <sharesVoted>110400</sharesVoted>
    <sharesOnLoan>0</sharesOnLoan>
    <vote>
      <voteRecord>
        <howVoted>FOR</howVoted>
        <sharesVoted>110400</sharesVoted>
        <managementRecommendation>FOR</managementRecommendation>
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    <voteSeries></voteSeries>
    <voteOtherInfo></voteOtherInfo>
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  <proxyTable>
    <issuerName>CURIS, INC.</issuerName>
    <cusip>231269309</cusip>
    <isin>US2312693094</isin>
    <figi></figi>
    <meetingDate>05/21/2024</meetingDate>
    <voteDescription>To approve an advisory vote on executive compensation.</voteDescription>
    <voteCategories>
      <voteCategory>
        <categoryType>SECTION 14A SAY-ON-PAY VOTES</categoryType>
      </voteCategory>
    </voteCategories>
    <voteSource>ISSUER</voteSource>
    <sharesVoted>421951</sharesVoted>
    <sharesOnLoan>0</sharesOnLoan>
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      <voteRecord>
        <howVoted>FOR</howVoted>
        <sharesVoted>421951</sharesVoted>
        <managementRecommendation>FOR</managementRecommendation>
      </voteRecord>
    </vote>
    <voteSeries></voteSeries>
    <voteOtherInfo></voteOtherInfo>
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  <proxyTable>
    <issuerName>ROCKET PHARMACEUTICALS, INC.</issuerName>
    <cusip>77313F106</cusip>
    <isin>US77313F1066</isin>
    <figi></figi>
    <meetingDate>06/13/2024</meetingDate>
    <voteDescription>Approval of the compensation of the Company's named executive officers, on a non-binding, advisory basis.</voteDescription>
    <voteCategories>
      <voteCategory>
        <categoryType>SECTION 14A SAY-ON-PAY VOTES</categoryType>
      </voteCategory>
    </voteCategories>
    <otherVoteDescription></otherVoteDescription>
    <voteSource>ISSUER</voteSource>
    <sharesVoted>204264</sharesVoted>
    <sharesOnLoan>0</sharesOnLoan>
    <vote>
      <voteRecord>
        <howVoted>FOR</howVoted>
        <sharesVoted>204264</sharesVoted>
        <managementRecommendation>FOR</managementRecommendation>
      </voteRecord>
    </vote>
    <voteSeries></voteSeries>
    <voteOtherInfo></voteOtherInfo>
  </proxyTable>
  <proxyTable>
    <issuerName>TG THERAPEUTICS, INC.</issuerName>
    <cusip>88322Q108</cusip>
    <isin>US88322Q1085</isin>
    <figi></figi>
    <meetingDate>06/14/2024</meetingDate>
    <voteDescription>An advisory vote to approve the compensation of our named executive officers.</voteDescription>
    <voteCategories>
      <voteCategory>
        <categoryType>SECTION 14A SAY-ON-PAY VOTES</categoryType>
      </voteCategory>
    </voteCategories>
    <voteSource>ISSUER</voteSource>
    <sharesVoted>62449</sharesVoted>
    <sharesOnLoan>0</sharesOnLoan>
    <vote>
      <voteRecord>
        <howVoted>FOR</howVoted>
        <sharesVoted>62449</sharesVoted>
        <managementRecommendation>FOR</managementRecommendation>
      </voteRecord>
    </vote>
    <voteSeries></voteSeries>
    <voteOtherInfo></voteOtherInfo>
  </proxyTable>
  <proxyTable>
    <issuerName>BRIDGEBIO PHARMA INC.</issuerName>
    <cusip>10806X102</cusip>
    <isin>US10806X1028</isin>
    <figi></figi>
    <meetingDate>06/21/2024</meetingDate>
    <voteDescription>To cast a non-binding, advisory vote to approve the compensation of the Company's named executive officers.</voteDescription>
    <voteCategories>
      <voteCategory>
        <categoryType>SECTION 14A SAY-ON-PAY VOTES</categoryType>
      </voteCategory>
    </voteCategories>
    <voteSource>ISSUER</voteSource>
    <sharesVoted>23328</sharesVoted>
    <sharesOnLoan>0</sharesOnLoan>
    <vote>
      <voteRecord>
        <howVoted>FOR</howVoted>
        <sharesVoted>23328</sharesVoted>
        <managementRecommendation>FOR</managementRecommendation>
      </voteRecord>
    </vote>
    <voteSeries></voteSeries>
    <voteOtherInfo></voteOtherInfo>
  </proxyTable>
</proxyVoteTable>
